Ever since Cady can remember, Nana has been there for her. Whether Cady was stuck at the top of a slide, or stranded in the middle of an ice-skating rink, or hit in the head with a tennis ball, Nana was always the first to her rescue. She's never let Cady down. But the summer before seventh grade, it looks as if that might happen. Strong, funny, feisty Nana has cancer, a disease that threatens to take away her humor, her strength, and, ultimately, her life. And as Cady watches her friend change, she's not sure she knows, or wants to know, this new Nana--until she realizes that now it is Nana who needs to be rescued.