Emma has been lonely all her life growing up in a neighborhood with no other kids--until the day two sets of sisters move to her street! The girls immediately form a club, only to discover that something mysterious is going on. They've each always had special talents, but when they work together, it's almost like their skills become superpowers. Now the sisterhood is ready to help their neighborhood thrive, as long as they can keep the spooky Ms. Wigglestoot from discovering their secret.