Sixteen-year-old Clover, a high-functioning autistic girl, and her brother West live in a post-apocalyptic U.S. sixteen years after a virus wiped out most of the world's population and survivors living in walled cities rely on a daily dose of medicine to keep the virus at bay. This miracle cure, and everything else, is controlled by the Company. Clover is drafted as a Time Mariner and sent two years into the future to bring back news and information, but when she discovers that West's life is in danger, the siblings must go on the run, take on the powerful Company, and maybe even start a revolution.